IAL System Duo 1ml

£69.00

Availability: In stock

£69.00
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Ial-System® DUO is a sterile, light, transparent, monophasic gel based

This product is of European origin
VAT Exempt

Ial-System DUO

 
Ial-System® DUO is a sterile, light, transparent, monophasic gel based on HA with multiple cross-links, created using the patented MUCH Technology ™ technology.

  • Transparent, sterile, monophasic viscous gel.
  • Total content of HA: 25 mg / ml.
  • The content of free BDDE: <0.2 ppm.
  • Bacterial endotoxin: <0.02 EU / mg.
  • pH 5-7.

 
Ial-System ® DUO consists of stabilized HA (concentration 25 mg / ml) and HA-ACP ether (25% of the total volume). Has a dense consistency, while remaining a plastic, elastic, transparent gel. 
The presence of two types of chemical modification (stabilization of BDDE and ether bond) provides two types of biodegradation of HA, which leads to the following clinical effects:

  • short-term biostimulating effect due to the release of native HA (in the form of ACP).
  • long-lasting effect of volume increase due to increased resistance to destruction of HA, cross-linked with BDDE.

 

Role of ACP: biological function:

  • HA interacts with CD44 receptors involved in the adhesion, proliferation and differentiation of fibroblasts and mesenchymal stem cells (MSC) contained in adipose tissue;
  • hydrolysis of ACP attracts macrophages that release growth factors that stimulate the growth of fibroblasts and the formation of a new extracellular matrix;
  • HA, released from the ACP, connecting to the CD44 receptors, inhibits the formation of collagenase MMP-13 by the action of IL-1β cytokine.


The role of crosslinked HA: the chemical network plays a "protective role", reducing the rate of hydrolysis of the ACP. The type and degree of cross-linking provide the effect of maintaining the volume for 6-8 months. 
Ial-System® DUO is available in a kit containing 1 syringe containing 1.0 ml sterile gel and two disposable needles (27G) in separate blister packs. 
 
Application. 
Ial-System® DUO is recommended for correcting the following zones:

  • nasolabial folds;
  • lips (mainly to increase the volume);
  • cheek-cheek area and chin (change in shape);
  • the back of the hands, the neck and shoulders;
  • the glabella region.
barcode No
Size 1 ML
Licensed Product No
Registration Required No
Country Origin This product is of European origin
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